Pesquisa sobre:
RHO-ASSOCIATED KINASES
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DeCS
Descritor
Inglês
:
rho-Associated Kinases
Descritor
Espanhol
:
Quinasas Asociadas a rho
Descritor
Português
:
Quinases Associadas a rho
Sinônimos
Inglês
:
rho-Associated Kinase
Categoria:
D08.811.913.696.620.682.700.814
D12.644.360.590
D12.776.476.595
Definição
Inglês
:
A group of intracellular-signaling
serine
threonine
kinases that bind to
RHO GTP-BINDING PROTEINS
. They were originally found to mediate the effects of
rhoA GTP-BINDING PROTEIN
on the formation of
STRESS FIBERS
and
FOCAL ADHESIONS
.
Rho-associated kinases
have specificity for a variety of
substrates
including
MYOSIN-LIGHT-CHAIN PHOSPHATASE
and
LIM KINASES.
Nota Histórica
Inglês
:
2008
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
52746
Identificador Único:
D054460
Ocorrência na BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
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